{"id":21813,"date":"2024-09-10T21:12:57","date_gmt":"2024-09-10T19:12:57","guid":{"rendered":"https:\/\/www.pmfst.unist.hr\/znanost\/?p=21813"},"modified":"2024-12-06T12:48:05","modified_gmt":"2024-12-06T11:48:05","slug":"grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2","status":"publish","type":"post","link":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/","title":{"rendered":"Grupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva"},"content":{"rendered":"
[vc_row][vc_column][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]Voditelji grupe<\/b>[\/mk_title_box][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18822″][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18619″][\/vc_column][vc_column width=”2\/6″][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]\u010clanovi grupe<\/b>[\/mk_title_box][mk_custom_box padding_vertical=”10″][mk_custom_list style=”mk-moon-user-3″]\n
    \n
  • \u00a0 \u00a0<\/span>dr. sc. Ines Primo\u017ei\u010d<\/li>\n
  • \u00a0 \u00a0 doc. dr. sc. Lucija Krce<\/li>\n
  • \u00a0 \u00a0 doc. dr. sc. Antonela Sovulj<\/li>\n
  • \u00a0 \u00a0 Doris Crn\u010devi\u0107, mag. edu. biol. et chem.<\/li>\n
  • \u00a0 \u00a0 Antonio Sablji\u0107, mag. chem.<\/li>\n
  • \u00a0 \u00a0 dr. sc. Andrea Paut i Tin Bobeta, mag. chem.<\/li>\n<\/ul>\n[\/mk_custom_list][\/mk_custom_box][\/vc_column][\/vc_row][vc_row][vc_column][mk_title_box color=”#1e73be” font_family=”none”]Odjel\/Katedra: <\/strong><\/p>\n

    Odjel za kemiju[\/mk_title_box][vc_column_text css=”.vc_custom_1725995515678{margin-bottom: 0px !important;}”]\n

    Opis istra\u017eivanja:<\/strong><\/h4>\n

    Interdisciplinarna grupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva okuplja znanstvenike iz podru\u010dja organske kemije, biokemije i biofizike. Znanstveni interes te djelovanje ove grupe obuhva\u0107a tri razli\u010dita smjera istra\u017eivanja. Prvi je sinteza te strukturna karakterizacija novih kvaternih amonijevih spojeva koji su \u010desto komponente antisepti\u010dkih i dezinfekcijskih sredstava. Procesu sinteze prethodi detaljan dizajn spojeva razli\u010ditih (hetero)cikli\u010dkih okosnica s pomno odabiranim funkcionalnim skupinama i supstituentima kako bi se dobile nove strukture pobolj\u0161anih fizikalnih i biolo\u0161kih svojstava. Drugi smjer istra\u017eivanja obuhva\u0107a opse\u017ena biolo\u0161ka ispitivanja kao \u0161to je detaljna analiza antimikrobne aktivnosti, potencijal razvoja rezistencije te ispitivanja citotoksi\u010dnosti na stanicama i na animalnom modelu. Tre\u0107i smjer istra\u017eivanja fokusiran je na mehanizam antibakterijskog djelovanja koji predstavlja zavr\u0161ni korak pri \u010demu se primjenjuju napredne tehnike i instrumenti koji poma\u017eu u razlikovanju bakteriostatskog, odnosno baktericidnog mehanizma djelovanja. Rezultati navedenih istra\u017eivanja, vrijedan su doprinos u podru\u010dju kemije kvaternih amonijevih spojeva, jer rezultiraju spoznajama koje mogu biti smjernica za nove generacije antimikrobnih spojeva.[\/vc_column_text][vc_column_text css=”.vc_custom_1725995543782{margin-bottom: 0px !important;}”]\n

    Partnerski potencijali:<\/strong><\/h4>\n

    Odjel za biologiju i Odjel za fiziku PMF-a Split, Kemijski odsjek, PMF Zagreb, Institut Ru\u0111er Bo\u0161kovi\u0107, Zagreb, Hrvatski zavod za javno zdravstvo, farmaceutska industrija, Selvita[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=”.vc_custom_1726614568222{margin-bottom: 0px !important;}”]\n

    Financijski i drugi potencijali:<\/strong><\/h4>\n

    institucijsko financiranje, programsko financiranje, HrZZ, europski istra\u017eiva\u010dki fondovi<\/p>\n

      \n
    • HrZZ 2020-02-2356 Discovery and development of new bioactive quaternary ammonium compounds derived from quinuclidine<\/li>\n
    • HrZZ DOK-2021-02 Razvoj karijera mladih istra\u017eiva\u010da – izobrazba novih doktora znanosti<\/li>\n
    • Prijave projekata mobilnosti asistenata i vi\u0161ih asistenata<\/li>\n
    • Priprema i prijava projekata na pozive europskih istra\u017eiva\u010dkih fondova\/Hrvatske zaklade za znanosti\/Bilateralnih projekata<\/li>\n
    • Prijava i sredstva institucijskih projekata (posebno za mlade znanstvenike)<\/li>\n<\/ul>\n[\/vc_column_text][vc_column_text css=”.vc_custom_1726614602691{margin-bottom: 0px !important;}”]Znanstveni ciljevi<\/strong> kojima se daje doprinos: Z-8, Z-9<\/p>\n
        \n
      • Z-1: Pobolj\u0161anje u\u010dinkovitosti znanstveno-istra\u017eiva\u010dkog rada (kori\u0161tenje znanstvenoistra\u017eiva\u010dke opreme i laboratorija)<\/li>\n
      • Z-2 Ja\u010danje uloge u znanstveno-istra\u017eiva\u010dkim kompetitivnim projektima (voditelj projekata Hrvatske zaklade za znanost)<\/li>\n
      • Z-4 Ja\u010danje ljudskih potencijala za znanstveno-istra\u017eiva\u010dki rad (osigurana sredstva za zapo\u0161ljavanje dva asistenta)<\/li>\n
      • Z-5 Ja\u010danje konkurentnosti mladih znanstvenika (izobrazba i usavr\u0161avanje mladih asistenata kroz projekt HrZZ, mentoriranje mladih znanstvenika, konzultiranje i voditeljstvo vi\u0161ih asistenata u pripremi institucijskih i kompetitivnih projekata)<\/li>\n
      • Z-7 Unaprje\u0111enje istra\u017eiva\u010dke infrastrukture (kroz projekt HrZZ-a osigurana su sredstva za odr\u017eavanje postoje\u0107e te nabavu nove znanstvene opreme)<\/li>\n
      • Z-8: Doprinos otvorenoj znanosti (istra\u017eiva\u010dki podatci generirani provedbom projekta ustupljeni su putem institucijskog repozitorija u skladu s planom upravljanja istra\u010dkim podacima po projektu HrZZ-a, rezultati istra\u017eivanja objavljeni su i objavljivat \u0107e se u \u010dasopisima otvorenog pristupa)<\/li>\n
      • Z-9: Ja\u010danje interdisciplinarnosti znanstvenog rada (kroz projekt umre\u017eeni su znanstvenici iz razli\u010ditih polja prirodnih znanosti (kemije, biologije i fizike))<\/li>\n
      • Z-10 Ja\u010danje diseminacije rezultata znanstvenih istra\u017eivanja (publiciranje radova u me\u0111unarodnim znanstvenim \u010dasopisima te prezentiranje radova na me\u0111unarodnim i doma\u0107im znanstvenim skupovima<\/li>\n<\/ul>\n

        Mjerljivi pokazatelji<\/strong> kojima se daje doprinos i vrijednost doprinosa: <\/strong><\/p>\n

          \n
        • R-Z-01: 3 (2 voditeljstva HrZZ i 1 suradnik na HrZZ)<\/li>\n
        • R-Z-02: 266 400,00 \u20ac (HrZZ)<\/li>\n
        • R-Z-03: 5-7<\/li>\n
        • R-Z-08: 1-2<\/li>\n
        • R-Z-09: 1 (doktorandica\/asistentica koja je upisala Doktorski studij kemije na PMF-u Zagreb i obranila temu doktorata)<\/li>\n
        • R-Z-10: 2-3 (2 HrZZ)<\/li>\n
        • R-Z-15: odr\u017eavanje postoje\u0107e istra\u017eiva\u010dke opreme (redoviti servis, sitni mali popravci itd.)<\/li>\n
        • R-Z-18: 1 interdiciplinarni teku\u0107i projekt HrZZ-a<\/li>\n
        • R-Z-F2 (mikrobiolo\u0161ka radionica i radionica iz masene spektrometrije organizirana za \u010dlanove istra\u017eiva\u010dkog tima na Fakultetu (sredstva za radionice osigurana su putem HrZZ-a)<\/li>\n
        • R-Z-F3: 2 (suradnja s kolegama na Odjelu za biologiju te Odjelu za fiziku)<\/li>\n
        • R-Z-F5: 3-5 (\u010dlanovi istra\u017eiva\u010dkog tima kroz provedbu projekta sudjelovat \u0107e na internim i vanjskim (me\u0111unarodnim) znanstvenim doga\u0111anjima)<\/li>\n
        • R-Z-F6: 5-7 (2 kompetitivna HrZZ, 3 institucijska)<\/li>\n
        • R-Z-F7: 1-3 (interni znanstveno-istra\u017eiva\u010dki projekt za mlade znanstvenike)<\/li>\n
        • R-Z-F10: 10-12<\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_column][\/vc_column]\n<\/div>","protected":false},"excerpt":{"rendered":"

          [vc_row][vc_column][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]Voditelji grupe[\/mk_title_box][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18822″][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18619″][\/vc_column][vc_column width=”2\/6″][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]\u010clanovi grupe[\/mk_title_box][mk_custom_box padding_vertical=”10″][mk_custom_list style=”mk-moon-user-3″] \u00a0 \u00a0dr. sc. Ines Primo\u017ei\u010d \u00a0 \u00a0 doc. dr. sc. Lucija Krce \u00a0 \u00a0 doc. dr. sc. Antonela Sovulj \u00a0 \u00a0 Doris Crn\u010devi\u0107, mag. edu. biol. et chem. \u00a0 \u00a0 Antonio Sablji\u0107, mag. chem. \u00a0 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"rs_blank_template":"","rs_page_bg_color":"","slide_template_v7":"","footnotes":""},"categories":[155,149],"tags":[],"poredak":[],"class_list":["post-21813","post","type-post","status-publish","format-standard","hentry","category-istrazivacke-grupe-odjela-za-kemiju","category-nove-istrazivacke-grupe"],"acf":[],"yoast_head":"\nGrupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva - Znanstvena djelatnost, PMF Split<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"hr_HR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Grupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva - Znanstvena djelatnost, PMF Split\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]Voditelji grupe[\/mk_title_box][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18822″][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18619″][\/vc_column][vc_column width=”2\/6″][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]\u010clanovi grupe[\/mk_title_box][mk_custom_box padding_vertical=”10″][mk_custom_list style=”mk-moon-user-3″] \u00a0 \u00a0dr. sc. Ines Primo\u017ei\u010d \u00a0 \u00a0 doc. dr. sc. Lucija Krce \u00a0 \u00a0 doc. dr. sc. 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Znanstvena djelatnost, PMF Split","robots":{"index":"noindex","follow":"follow"},"og_locale":"hr_HR","og_type":"article","og_title":"Grupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva - Znanstvena djelatnost, PMF Split","og_description":"[vc_row][vc_column][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]Voditelji grupe[\/mk_title_box][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18822″][\/vc_column][vc_column width=”2\/6″][mk_employees style=”boxed” column=”1″ employees=”18619″][\/vc_column][vc_column width=”2\/6″][mk_title_box color=”#1e73be” margin_bottom=”0″ font_family=”none”]\u010clanovi grupe[\/mk_title_box][mk_custom_box padding_vertical=”10″][mk_custom_list style=”mk-moon-user-3″] \u00a0 \u00a0dr. sc. Ines Primo\u017ei\u010d \u00a0 \u00a0 doc. dr. sc. Lucija Krce \u00a0 \u00a0 doc. dr. sc. Antonela Sovulj \u00a0 \u00a0 Doris Crn\u010devi\u0107, mag. edu. biol. et chem. \u00a0 \u00a0 Antonio Sablji\u0107, mag. chem. \u00a0 […]","og_url":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/","og_site_name":"Znanstvena djelatnost, PMF Split","article_publisher":"https:\/\/www.facebook.com\/pmfst\/","article_published_time":"2024-09-10T19:12:57+00:00","article_modified_time":"2024-12-06T11:48:05+00:00","author":"autor","twitter_card":"summary_large_image","twitter_creator":"@PmfSplit","twitter_site":"@PmfSplit","twitter_misc":{"Napisao\/la":"autor","Procijenjeno vrijeme \u010ditanja":"4 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/#article","isPartOf":{"@id":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/"},"author":{"name":"autor","@id":"https:\/\/www.pmfst.unist.hr\/znanost\/#\/schema\/person\/8c4957fe31fd46303be41a1bd068040a"},"headline":"Grupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva","datePublished":"2024-09-10T19:12:57+00:00","dateModified":"2024-12-06T11:48:05+00:00","mainEntityOfPage":{"@id":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/"},"wordCount":838,"publisher":{"@id":"https:\/\/www.pmfst.unist.hr\/znanost\/#organization"},"articleSection":["Istra\u017eiva\u010dke grupe odjela za kemiju","Nove istra\u017eiva\u010dke grupe"],"inLanguage":"hr"},{"@type":"WebPage","@id":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/","url":"https:\/\/www.pmfst.unist.hr\/znanost\/grupa-za-sintezu-i-bioloska-ispitivanja-novih-kvaternih-amonijevih-spojeva-2\/","name":"Grupa za sintezu i biolo\u0161ka ispitivanja novih kvaternih amonijevih spojeva - 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